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When the dosage form has a reduced density compared to gastric fluids, it'll float on a major on the stomach content, permitting for an elevated time span to release the drug before the system is emptied out into compact intestine. The gastric fluid contains a density of about 1gm/cm3. When the density of your dosage type is lower than that, it is
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A buffer that contains around equal quantities of a weak acid and its conjugate base in solution is Similarly powerful at neutralizing possibly additional base or extra acid. This really is revealed in Figure (PageIndex 2 ) for an acetic acid/sodium acetate buffer.Not specifying when to evaluate pH: Addition of natural and organic solvents to buffe
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